Holmes and Watson investigate the legend of a supernatural hound, a beast that may be stalking a young heir on the fog-shrouded moorland that makes up his estate.
Sherlock Holmes takes a vacation and visits his old friend Sir Henry Baskerville. His vacation ends when he suddenly finds himself in the middle of a double-murder mystery. Now he's got to find Professor Moriarty and the horse Silver Blaze before the great cup final horse race.
When a Nazi saboteur jeeringly predicts to the nation new depredations, via their radio 'Voice of Terror', the Intellegence Inner Council summons Sherlock Holmes to help in the crisis.
Sherlock Holmes and Doctor Watson must protect a Swiss inventor of an advanced bomb sight from falling into German hands.
During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.
Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider.
When a gentlewoman is found dead with her throat torn out, the villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
When a valuable pearl with a sinister reputation is stolen, Sherlock Holmes must investigate its link to a series of brutal murders.
When members of the Good Comrades club start being killed, Holmes is called to their Scottish mansion to investigate. Before a victim is killed, he receives an envelope with orange pips. After each death, the life insurance of the victim is shared among the survivors. In all cases the identification is difficult, with the victims only identified by items of clothing or, in one case, a tattoo. Inspector Lestrade receives a note from a local shopkeeper, who says he has a clue. When Lestrade, Holmes and Watson visit, they find the shopkeeper killed. Holmes exhumes one of the graves and find the coffin empty. They return to the mansion and find a sixth member has been murdered and the sole surviving member, Bruce Alastair, arrested. Watson goes missing shortly afterwards and Holmes and Lestrade locate a hidden tunnel which leads to an old smugglers' cave: inside they find the six missing members of the club who had all faked their deaths in order to cash in on the life insurance, using the corpses of recently dead villagers.
Holmes and Watson are consulted by Inspector Gregson of Scotland Yard to assist with the "finger murders", where young women have been murdered and one of their fingers has been removed. Holmes and Gregson see Sir George Fenwick at Pembroke House with an attractive woman, Lydia Marlowe. The couple leave and Fenwick is drugged and later wakes to find another murder has been committed and that the finger is in his pocket. He returns to Marlowe's flat where he meets Professor Moriarty, who blackmails him. The following day Fenwicke is found killed, clutching a matchbook from Pembroke House. After an attempt on Holmes's life by a hypnotised former soldier, Holmes and Watson visit the Mesmer Club, whose members are all interested in hypnotism. Marlowe also visits the club and lures Holmes back to her flat where she hypnotises him. Moriarty instructs the hypnotised Holmes to write a suicide note and leads him to the terrace in order that the detective should commit suicide. Watson and the police raid the flat and Holmes reveals that he was not hypnotised after all. As he is being arrested, Moriarty tries to jump to the building next door, but instead falls, apparently to his death.
Holmes is recruited to escort the heir to a European throne safely back to his homeland after his father's assassination.
When a Nazi saboteur jeeringly predicts to the nation new depredations, via their radio 'Voice of Terror', the Intellegence Inner Council summons Sherlock Holmes to help in the crisis.
Music boxes are sold at an auction and the buyers of these seem to get killed. Holmes and Watson are called to investigate these killings and learn that a young women, who is the leader of a criminal gang has something to do with them. After attempting to kill Holmes, she is caught at the end.